. Author manuscript; available in PMC: 2019 Apr 24.

Published in final edited form as: Biometrics. 2018 Jun 5;74(4):1438–1449. doi: 10.1111/biom.12910

Table 1. Analyses performed in each simulated data set. NCC indicates “nested case-control.”.

Analysis	Variables with missing data	Imputation	Analysis
	Case-cohort sample within a full cohort
Complete-data case-cohort	NA	NA	Case-cohort
Complete-data full cohort	NA	NA	Full cohort
Complete-case case-cohort	X₂	NA	Case-cohort
MI-approx: full-cohort approach	X₁, X₂	Full cohort	Full cohort
MI-SMC: full-cohort approach	X₁, X₂	Full cohort	Full cohort
MI-approx: intermediate approach	X₁, X₂	Full cohort	Case-cohort
MI-SMC: intermediate approach	X₁, X₂	Full cohort	Case-cohort
MI-approx: substudy approach	X₂	Case-cohort	Case-cohort
MI-SMC: substudy approach	X₂	Case-cohort	Case-cohort
	Nested case-control sample within a full cohort
Complete-data NCC	NA	NA	NCC
Complete-data full cohort	NA	NA	Full cohort
Complete-case NCC	X₂	NA	NCC
MI-approx: full-cohort approach	X₁, X₂	Full cohort	Full cohort
MI-SMC: full-cohort approach	X₁, X₂	Full cohort	Full cohort
MI-approx: intermediate approach	X₁, X₂	Full cohort	NCC
MI-SMC: intermediate approach	X₁, X₂	Full cohort	NCC
MI-approx: substudy approach	X₂	NCC	NCC
MI-SMC: substudy approach	X₂	NCC	NCC
MI matched set	X₂	NCC	NCC