Santilli 2015.
Methods |
Allocation: randomised Intervention model: parallel assignment Masking: open label |
Participants |
Condition: impaired glucose tolerance, impaired fasting glucose or newly diagnosed T2DM Enrolment: 29 Inclusion criteria: metformin‐treated obese participants with impaired glucose tolerance, impaired fasting glucose or newly diagnosed T2DM Exclusion criteria: NR |
Interventions |
Intervention(s): liraglutide, subcutaneous Comparator (s): placebo Duration of intervention: 4 months |
Outcomes |
Primary outcomes: not specified, assume: change in subcutaneous fat and visceral adipose tissue Secondary outcomes: not specified, assume: degree of non‐alcoholic fatty liver disease, weight loss, insulin sensitivity, β‐cell performance, C‐reactive protein, leptin, glycaemic measures |
Study details | Trial terminated early: no |
Publication details |
Language of publication: English Funding: NR Publication status: abstract |
Stated aim of study | Quote: "... we hypothesized that this class of drugs may exert additional cardiometabolic actions on top of those anticipated for lifestyle intervention‐mediated weight loss." |
Notes | Separate data for participants with intermediate hyperglycaemia are not yet available, but will be provided from the authors when the full article is published |