Table III.
Mean (standard error) demographic, neurocognitive, and medical outcomes for HIV+ individuals with subjective cognitive decline (SCI) and without SCI as defined by either Profile of Mood States (POMS) or Prospective and Retrospective Memory Questionnaire (PRMQ) impaired at 1.5 SD cutoffs.
| Variable | SCI (n = 32) | No SCI (n = 156) | P | Cohen’s d |
|---|---|---|---|---|
| Age (years) | 45.0 (1.9) | 46.3 (0.9) | .708 | .12 |
| Gender (% men) | 81.3 | 88.5 | .287 | .30 |
| Education (years) | 13.3 (0.4) | 13.8 (0.2) | .535 | .22 |
| Ethnicity (% Caucasian) | 50.0 | 64.7 | .160 | .13 |
| Estimated verbal IQ (WTAR) | 105.4 (1.9) | 105.6 (0.8) | .940 | .02 |
| Neuropsychological Global T-score | 52.0 (0.8) | 52.9 (0.4) | .212 | .20 |
| Learning T-score* | 51.9 (1.6) | 55.5 (0.6) | .023 | .42 |
| Memory T-score* | 51.6 (1.5) | 54.8 (0.6) | .025 | .41 |
| Attention T-score | 50.2 (1.4) | 50.5 (0.6) | .684 | .04 |
| Speed of Information Processing T-score | 52.6 (1.2) | 52.2 (0.5) | .769 | .06 |
| Executive Functions T-score | 52.9 (1.2) | 54.3 (0.6) | .311 | .20 |
| Motor Dexterity T-score | 52.6 (1.3) | 49.8 (0.7) | .112 | .34 |
| Major Depressive Disordera (%)♮ | 65.6 | 46.8 | .080 | .42 |
| Generalized Anxiety Disordera (%) | 15.6 | 10.9 | .544 | .22 |
| Substance Use Disordera (%)* Medical | 90.6 | 68.0 | .009 | .84 |
| Hepatitis C Virus (%) | 17.2 | 20.3 | .716 | .10 |
| Estimated duration of HIV infection (years) | 147.7 (16.3) | 164.3 (8.0) | .383 | .18 |
| Current CD4 count (cells/μL) | 536.9 (51.3) | 565.3 (22.8) | .579 | .10 |
| Nadir CD4 count (cells/μL) | 212.4 (24.9) | 206.1 (14.2) | .466 | .04 |
| AIDS (%) | 62.5 | 55.1 | .441 | .16 |
| ARV status (% prescribed) | 78.1 | 85.9 | .286 | .29 |
| Plasma HIV RNA (% detectable) | 25.8 | 27.6 | .834 | .05 |
| Among those prescribed ARV | 8.0 | 18.3 | .171 | .52 |
Note. Data represent mean (standard error) or valid population percentage values. Cohen’s d values for binary outcomes represent effect sizes converted from odds ratios. WTAR = Wechsler Test of Adult Reading; MIST = Memory for Intentions Screening Test; POMS = Profile of Mood States; HCV = hepatitis C virus; CD4 = cluster of differentiation; AIDS = acquired immunodeficiency syndrome; ARV = antiretroviral; iADL = instrumental activities of daily living; bADL = basic activities of daily living.
Lifetime diagnosis.
Any lifetime diagnosis of dependence on alcohol or illicit substances.
p < .05
p < .10