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. Author manuscript; available in PMC: 2020 Jan 8.
Published in final edited form as: Circulation. 2019 Jan 8;139(2):180–191. doi: 10.1161/CIRCULATIONAHA.118.035411

Table 5.

Improvement in Reclassification of 1-Year Stroke Risk in the Atherosclerosis Risk in Communities (ARIC) study.

CHA2DS2VASc P2-CHA2DS2VASc§
CHA2DS2VASc P2-CHA2DS2VASc§
<1% 1-2% >2% Total <1% 1-2% >2% Total
<1% 19 3* 0* 22 <1% 290 22 0 312
1-2% 3 9 4* 16 1-2% 167* 686 94 947
>2% 0 0 9 9 >2% 0* 290* 633 923
Total 22 12 13 47 Total 457 998 727 2182


Participants with stroke in 1 year Participants without stroke in 1 year
*

Favorable reclassification

Unfavorable reclassification

age (1 point for >65, 2 points for >75), sex (1 point for female), Heart Failure (1 point), hypertension (1 point), diabetes (1 point), previous myocardial infarction/peripheral artery disease (1 point), prevalent stroke/transient ischemic attack (2 points)

§

CHA2DS2VASc + abnormal P-wave axis (2 points)

Abbreviations: Category-based Net Reclassification Index (NRI), Relative Integrative Discrimination Improvement (IDI), TIA (transient ischemic attack)