PDGF |
Regranex (sodium carboxymethylcellulose gel) |
Mixing |
Diabetic patients with non-healing, full thickness diabetic foot ulcers |
23 |
PDGF |
Chitosan gel |
Mixing |
Rats–streptozotocin induced diabetes (full thickness wound) |
24 |
PDGF |
Collagen-chitosan gel |
Mixing |
Rats (dorsal wound) |
22 |
PDGF or FGF |
Polyethylene glycol |
Mixing |
Db/db mice (full thickness wound) |
21 |
FGF-2 |
Heparin-poly(ethylene argininylaspartate digylceride) matrix |
Coacervation |
Mice (full excisional wound) |
33 |
FGF |
Polyurethane hydrogel |
Mixing |
Mice and rats (full excisional wound) |
32 |
EGF or FGF |
Hyaluronate-collagen dressing |
Mixing, lyophilization |
Mice–streptozotocin induced diabetes (full thickness wound) |
26 and 27
|
EGF |
Polyvinyl alcohol-alginate gel |
Mixing, cross-linking |
Rats–streptozotocin induced diabetes (full thickness wound) |
28 |
EGF |
Pluronic-chitosan gel |
Mixing, cross-linking |
Mice–streptozotocin induced diabetes (dorsal burn) |
25 |
EGF |
Hyaluronate |
Aldehyde-amine conjugation |
Rats (full excisional wound) |
30 |
EGF |
Poly-lactic-co-glycolic acid |
Electrospinning nanofibers |
Db/db mice (full thickness wound) |
31 |
VEGF DNA |
Chitosan scaffolds |
Freeze dried chitosan soaked in DNA solution |
Rats (full excisional wound) |
35 |
VEGF |
Alginate microspheres |
Microencapsulation, ion exchange |
Rat (incision in groin) |
36 |
PRP |
Platelet gel |
Thrombin and calcium activation |
Diabetic patients with non-healing foot ulcers |
44 |