Rodent |
• Strong understanding of genetic makeup |
• Skin characteristics present differences in the healing mechanism |
• Multiple specialized models available |
• Differences in hair growth |
• Chronic healing models available |
• High physical activity of animal can impact wound healing environment |
• Relatively low cost to house and maintain |
• Irrelevant wound size |
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• Simple surgical operations |
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Pig |
• Skin is similar to humans |
• Lack of specialized models |
• Comparable healing characteristics to humans |
• Ethical considerations |
• Generation of wounds at relevant scales |
• Complex surgical operations |
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• High cost to house and maintain |
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• Need for specialized facilities |