FIG. 3.
Influence of driving pressure on the deformation behavior of cells in MS-DC. (a) Three point moving average of DI as a function of x-position in the channel for the breast cancer cell line MCF7 at driving pressures 10 kPa (black triangles), 15 kPa (blue circles), 25 kPa (red squares), and 30 kPa (purple diamonds). Each data point on the curves is the mean DI of ≥52 cells taken from all of the ten channels with cell size 0.85 < Dc/Dh < 0.95. The vertical dashed line represents the length L of the test section of the channel. (b) DI as a function of driving pressure for the breast cancer cell line MCF7. Each point represents the measured mean DI of the cells (≥52) with the same bin size 0.85 < Dc/Dh < 0.95 and the connected line is the linear fit of the data with R2 = 0.9303. The horizontal dashed lines show the maximum error limit in DI measurements.