Review	Condition treated	Studies	Participants	Topical intervention	Comparators	Assessment time (weeks)
Acute pain conditions
Derry 2014b	Strains, sprains, low back pain	6	697	Salicylate rubefacients	Placebo and active	1
Derry 2015	Strains and sprains	61	9001	NSAID	Placebo and active	1
Acute and chronic pain conditions
Cumpston 2009	Rotator cuff disease or chronic tendinopathy	3	121	Glyceryl trinitrate	Placebo	1 ‐ 24
Pattanittum 2013	Lateral elbow pain	15	759	NSAID	Placebo	2 ‐ 4
Chronic pain conditions
Cameron 2011	Rheumatoid arthritis	22	1243	Herbal remedies	Placebo and active	Up to 26
Cameron 2013	Osteoarthritis	7	785	Herbal remedies	Placebo and active	Up to 4
Cui 2010	Neck pain due to degenerative disease	4	1100	Herbal remedies	Placebo and active	Up to 4
Derry 2012	Neuropathic pain	6	389	Topical capsaicin low‐concentration	Placebo	6‐8
Derry 2014a	Neuropathic pain	12	508	Lidocaine	Placebo	From a single dose up to 12 weeks
Derry 2014b	Chronic musculoskeletal conditions	10	671	Salicylate rubefacients	Placebo and active	2
Derry 2016	Chronic musculoskeletal conditions	39	10631	NSAID	Placebo and active	2 ‐ 12
Derry 2017	Neuropathic pain	8	2488	Topical capsaicin high‐concentration	Placebo	8 ‐ 12
Otlean 2014	Low back pain	14	2050	Herbal remedies	Placebo and active	Typically 3
Wrzosek 2015	Neuropathic pain	2	344	Clonidine	Placebo	8 ‐ 12