Abdelmassih 2006.
Methods | Prospective randomised study, single centre. Randomisation method: not stated. Power analysis: not stated. Study period: not stated. Sample size: 206 women. Conflict of interest: not stated. |
|
Participants | Normagonadotropic women with an indication for IVF/ICSI. Age < 35 years. No available baseline characteristics to compare. |
|
Interventions | Luteal started pituitary downregulation with GnRH agonist. Standard treatment: from cycle day 2 onward daily 225 IU/L rFSH subcutaneous. Experimental treatment: from cycle day 7 onward daily additional 75 IU/L rLH until ovulation triggering with hCG. |
|
Outcomes | Primary endpoints:
Secondary endpoint:
|
|
Notes | Abstract only. Funding: not stated |
|
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Method of randomization not stated. |
Allocation concealment (selection bias) | Unclear risk | Method of allocation concealment not stated. |
Blinding of participants and personnel (performance bias) All outcomes | Low risk | Non‐blinding not likely to affect the outcomes of interest as they are objectively assessed. |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | Those who administered the intervention were not blinded but non‐blinding of outcome assessment not likely to affect the outcomes of interest as they are objectively assessed. |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Only abstract available. |
Selective reporting (reporting bias) | Unclear risk | Study protocol not available, no live birth rates. |
Other bias | Unclear risk | Insufficient information to make a conclusive judgement. |