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. 2017 May 10;2017(5):CD006185. doi: 10.1002/14651858.CD006185.pub4

Van Nunen 2012.

Methods RCT
 Method of randomisation: stated as block randomisation
 Blinding of outcome assessors: no
 Adverse events: none described
 Deaths: none
 Dropouts: none
 ITT: unknown
Participants Country: Hong Kong, China
 50 participants (30 in treatment group , 20 in control group)
 Non‐ambulatory at study onset (intervention group: 3 , control group: 2 )
Mean age: 53 years
 Inclusion criteria: unknown
 Exclusion criteria: unknown
Interventions 2 arms
  • 60‐minute sessions of gait training 2 times a week with the Lokomat, 60‐minute sessions of overground gait training 3 times a week for 8 weeks

  • 60‐minute sessions of overground gait training without device 5 times a week for 8 weeks

Outcomes Outcomes were assessed at baseline and after 8 weeks:
  • Walking speed

  • FAC

  • Berg Balance Scale

  • Rivermead Mobility Index

  • Fugl‐Meyer Leg Score

Notes Published and unpublished data provided by the authors.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Unclear
Allocation concealment (selection bias) Low risk A person not involved in the study was asked to draw 1 of the opaque envelopes inside which group assignment was established each time a new participant entered the study.
Blinding of outcome assessment (detection bias) 
 All outcomes High risk No
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Unclear