Zhu 2017.
| Methods | RCT, parallel‐group design. Single‐centre study |
| Participants | Total number of randomized participants: 49 Setting: China Inclusion criteria: invasive MV; ready for extubation Exclusion criteria: none reported |
| Interventions | Intervention group (HFNC): n = 25 Control group (NIV): n = 24 |
| Outcomes | All outcomes reported: ABG; sputum viscosity; nasal and facial pressure ulcers within 7 days; reintubation; change of therapy Outcomes relevant to this review: ABG; nasal and facial pressure ulcers; reintubation; change of therapy |
| Notes | Contact: Zhu Zhengfang, Department of Intensive Medicine, Tenth People's Hospital, Tongji University, Shanghai, 200072 Study dates: 1 January to 31 December 2016 We did not source the full text of this study which was published in Chinese; we have taken the current information from the English abstract. This study requires translation into English in order to be incorporated into the review. We will seek translation when completing the next review update. |
ABG: arterial blood gas AECOPD: acute exacerbation of COPD ARF: acute respiratory failure BiPAP: bilevel positive airway pressure CAM‐ICU: confusion assessment method for the ICU COPD: chronic obstructive pulmonary disease CPAP: continuous positive airway pressure FiO2: fraction of inspired oxygen HCO3: bicarbonate HDU: high dependency unit HFNC: high‐flow nasal cannulae ICU: intensive care unit IPAP: inspiratory positive airway pressure MV: mechanical ventilation NIV: non‐invasive ventilation PaCO2: partial pressure of carbon dioxide in arterial blood PaO2: partial pressure of oxygen in arterial blood pH: potential of hydrogen PEEP: positive end expiratory pressure RCT: randomized controlled trial RASS: Richmond agitation‐sedation score SpO2: oxygen saturation