Table 6. Top gene ontology enrichment results for ventral tegmental area mega module bisque.
| Category | Name | p-value | q-value Bonferroni | Hit Count in Query List | Hit Count in Genome | Hit in Query List |
|---|---|---|---|---|---|---|
| GO: Cellular Component | nucleolus | 6.41E-07 | 1.24E-04 | 17 | 894 | ZNF106, NEK2, EEF1D, RPL36, PNKP, SELENBP1, ZNF655, RPS9, WRN, GATA3, ZFHX3, RORC, DGCR8, TTC3, ARNTL2, NEK11, RPL18 |
| eukaryotic translation elongation factor 1 complex | 1.27E-04 | 2.47E-02 | 2 | 4 | EEF1D, EEF1A2 | |
| GO: Molecular Function | ubiquitin-protein transferase activity | 4.98E-07 | 1.33E-04 | 12 | 414 | RC3H2, TRAF4, UBE2K, TRIM2, TRIM25, TRIM9, HECW2, TRIM8, UBE2S, RNF114, TTC3, TRIM37 |
| ubiquitin-like protein transferase activity | 9.70E-07 | 2.59E-04 | 12 | 441 | RC3H2, TRAF4, UBE2K, TRIM2, TRIM25, TRIM9, HECW2, TRIM8, UBE2S, RNF114, TTC3, TRIM37 | |
| acid-amino acid ligase activity | 3.42E-06 | 9.12E-04 | 9 | 259 | RC3H2, TRIM2, TRIM25, TRIM9, HECW2, TRIM8, RNF114, TTC3, TRIM37 | |
| ligase activity, forming carbon-nitrogen bonds | 9.78E-06 | 2.61E-03 | 9 | 295 | RC3H2, TRIM2, TRIM25, TRIM9, HECW2, TRIM8, RNF114, TTC3, TRIM37 | |
| tubulin-glycine ligase activity | 1.87E-05 | 5.00E-03 | 8 | 244 | RC3H2, TRIM2, TRIM9, HECW2, TRIM8, RNF114, TTC3, TRIM37 | |
| protein-glycine ligase activity | 1.87E-05 | 5.00E-03 | 8 | 244 | RC3H2, TRIM2, TRIM9, HECW2, TRIM8, RNF114, TTC3, TRIM37 | |
| protein-glycine ligase activity, initiating | 1.87E-05 | 5.00E-03 | 8 | 244 | RC3H2, TRIM2, TRIM9, HECW2, TRIM8, RNF114, TTC3, TRIM37 | |
| coenzyme F420-0 gamma-glutamyl ligase activity | 1.87E-05 | 5.00E-03 | 8 | 244 | RC3H2, TRIM2, TRIM9, HECW2, TRIM8, RNF114, TTC3, TRIM37 | |
| ribosomal S6-glutamic acid ligase activity | 1.87E-05 | 5.00E-03 | 8 | 244 | RC3H2, TRIM2, TRIM9, HECW2, TRIM8, RNF114, TTC3, TRIM37 | |
| coenzyme F420-2 alpha-glutamyl ligase activity | 1.87E-05 | 5.00E-03 | 8 | 244 | RC3H2, TRIM2, TRIM9, HECW2, TRIM8, RNF114, TTC3, TRIM37 | |
| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity | 1.87E-05 | 5.00E-03 | 8 | 244 | RC3H2, TRIM2, TRIM9, HECW2, TRIM8, RNF114, TTC3, TRIM37 | |
| protein-glycine ligase activity, elongating | 1.87E-05 | 5.00E-03 | 8 | 244 | RC3H2, TRIM2, TRIM9, HECW2, TRIM8, RNF114, TTC3, TRIM37 | |
| tubulin-glutamic acid ligase activity | 2.05E-05 | 5.46E-03 | 8 | 247 | RC3H2, TRIM2, TRIM9, HECW2, TRIM8, RNF114, TTC3, TRIM37 | |
| protein-glutamic acid ligase activity | 2.17E-05 | 5.79E-03 | 8 | 249 | RC3H2, TRIM2, TRIM9, HECW2, TRIM8, RNF114, TTC3, TRIM37 | |
| ligase activity | 2.38E-05 | 6.35E-03 | 10 | 415 | LIG3, RC3H2, TRIM2, TRIM25, TRIM9, HECW2, TRIM8, RNF114, TTC3, TRIM37 | |
| DNA helicase activity | 2.43E-04 | 6.49E-02 | 4 | 65 | ERCC2, GTF2H4, RAD54B, WRN | |
| Pathway | Eukaryotic Translation Elongation | 1.67E-04 | 8.37E-02 | 5 | 98 | EEF1D, RPL36, RPS9, EEF1A2, RPL18 |
Functional enrichment results from ToppFun for Ventral Tegmental Area Mega Module Bisque, where Bonferroni-corrected p<0.1.