Important benefit or harm	Less important benefit or harm	No important benefit/harm or null effect
High‐quality evidence	Improves/decreases/prevents/leads to [outcome]	Improves slightly/decreases slightly/leads to slightly fewer (more) [outcome]	Results in little or no difference in [outcome]
Moderate‐quality evidence	Probably improves/decreases/prevents/leads to [outcome]	Probably improves slightly/decreases slightly/leads to slightly fewer (more) [outcome]	Probably leads to little or no difference in [outcome]
Low‐quality evidence	May improve/decrease/prevent/lead to [outcome]	May slightly improve/slightly decrease/lead to slightly fewer (more) [outcome]	May lead to little or no difference in [outcome]
Very low‐quality evidence	It is uncertain whether [intervention] improves, decreases, prevents, leads to [outcome] because the quality of the evidence is very low
No data or no studies	[Outcome] was not measured or was not reported, or no studies were found that evaluated the impact of [intervention] on [outcome]