4. Diagnostic accuracy estimates for colour duplex ultrasound and contrast‐enhanced colour duplex ultrasound.
Imaging method |
Summary sensitivity % (95% CI) |
Summary specificity % (95% CI) |
DOR (95% CI) |
LR+ (95% CI) | LR‐ (95% CI) |
Studies with accuracy estimates based on number of individual participants | |||||
CDUS (16 studies) | 82 (66 to 91) | 93 (87 to 96) | 56 (19 to 164) | 11.0 (6.0 to 20.0) | 0.19 (0.100 to 0.39) |
CE‐CDUS (11 studies) | 94 (85 to 98) | 95 (90 to 98) | 299 (95 to 935) | 19.5 (9.1 to 41.7) | 0.07 (0.03 to 0.16) |
Subgroup analysis 1: diagnostic performance of studies that estimated accuracy before and after administration of contrast (7 studies; analyses based on number of individual participants) | |||||
CDUS | 67 (47 to 83) | 94 (80 to 99) | 35 (5 to 246) | 12.0 (2.8 to 51.8) | 0.34 (0.18 to 0.63) |
CE‐CDUS | 97 (92 to 99) | 95 (85 to 98) | 531 (131 to 2147) | 17.7 (6.0 to 51.6) | 0.03 (0.01 to 0.09) |
Subgroup analysis 2: diagnostic performance of CE‐CDUS for type I and type III endoleaks | |||||
CE‐CDUS (7 studies) | 97 (81 to 99) | 99 (96 to 100) | 7073 (254 to 196,804) | 220.7 (25.9 to 1875.5) | 0.031 (0.004 to 0.22) |
Studies with accuracy estimates based on scan performed | |||||
CDUS (18 studies) | 72 (55 to 85) | 95 (90 to 96) | 37 (16 to 87) | 11.1 (6.8 to 18.1) | 0.29 (0.17 to 0.51) |
CE‐CDUS (8 studies) | 91 (68 to 98) | 89 (71 to 96) | 77 (9 to 605) | 8.2 (2.7 to 24.6) | 0.11 (0.03 to 0.43) |
Studies with accuracy estimates based on scan performed (excluding outliersMcWilliams 2002 and Nagre 2011) | |||||
CDUS (16 studies) | 77 (64 to 87) | 93 (89 to 96) | 48 (21 to 110) | 11.7 (6.8 to 20.0) | 0.24 (0.14 to 0.41) |
CE‐CDUS (6 studies) | 93 (84 to 97) | 91 (70 to 98) | 125 (23 to 689) | 9.9 (2.7 to 36) | 0.08 (0.03 to 0.19) |
CDUS: colour duplex ultrasound; CE‐CDUS: contrast‐enhanced colour duplex ultrasound; CI: confidence interval; DOR: diagnostic odds ratio; LR+: positive likelihood ratio; LR‐: negative likelihood ratio; NE: not estimable.