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. 2017 May 25;2017(5):CD012144. doi: 10.1002/14651858.CD012144.pub2
Study Reason for exclusion
Boeer 1991 This is an extension phase of Dickmann 1988 that introduces non‐randomised data to the previously published data.
CAST 1997 This trial included some people with ICH who were randomised prior to CT. These data were not available in the original manuscript. We had hoped that there would be useable data published in the Keir 2002 systematic review, but this did not separate primary ICH from haemorrhagic transformations of acute ischaemic stroke and we were therefore unable to include data from CAST 1997 in this review.
Frontera 2014 This is a controlled clinical trial that was not randomised.
IST 1997 This trial included several hundred participants with ICH who were randomised prior to CT. These data were not available in the original manuscript. We had hoped that data from the Keir 2002 systematic review or the published individual data forms (Sandercock 2011) would yield useable data for this review, but Keir 2002 did not report primary ICH separately from haemorrhagic expansion of an acute ischaemic stroke, and after contacting the chief investigator of IST 1997 we discovered that it was not possible to extract data on primary ICH separately.
Li 2013 The intervention randomised in this study is transfusion of frozen apheresis platelets in participants on aspirin and with ICH.
Venturelli 2014 This is a post hoc analysis of the INTERACT2 trial. The intervention that is the subject of this analysis, prophylactic subcutaneous heparin after ICH, was not randomly assigned in INTERACT2. Therefore, this analysis is observational in nature.
Yan 2014 The participant group did not have primary ICH; it was a cohort of people with and without cerebral microbleeds and haemorrhagic transformation, with acute ischaemic stroke following rtPA treatment.

CT: computed tomography
 ICH: intracerebral haemorrhage
 rtPA: Recombinant tissue plasminogen activator