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. 2019 Apr 12;17(4):e3000046. doi: 10.1371/journal.pbio.3000046

Fig 2. Coexpression analysis between EET and ENDO.

Fig 2

Distribution of the correlation coefficients for genes expressed in EET and CAR tissues (A) or ICAR tissues (B). (C) Number of genes expressed in EET, CAR tissues, or ICAR tissues that participate in significant correlation connections involving EET and ENDO. (D) Dendrogram of EET and CAR tissues formed by genes with strong coexpression. (E) Scatterplot of pairs of genes expressed in EET and CAR tissues with at least one gene involved in “mRNA processing” or “chromatin organization.” (F) Scatterplot of pairs of genes expressed in EET and CAR tissues and highly correlated with at least one gene involved in “RNA transport pathway.” The data underlying each panel on Fig 2 can be obtained with the scripts presented on S1 Code. CAR, caruncular; CDAN1, codanin 1; CEP44, centrosomal protein 44; ECSIT, ECSIT signaling integrator; EET, extraembryonic tissue; eFDR, empirical false discovery rate; EIF4E, eukaryotic translation initiation factor 4E; ENDO, endometrium; FPKM, fragments per kilobase per million reads; FOXJ2, forkhead box J2; GEMIN6, gem-nuclear-organelle–associated protein 6; ICAR, intercaruncular; INTS13, integrator complex subunit 13; KPNB1, karyopherin subunit beta 1; LYPLA1, acyl-protein thioesterase 1; MAGOHB, protein mago nashi homolog 2; MAP4K2, mitogen-activated protein kinase kinase kinase kinase 2; MIEF1, mitochondrial elongation factor 1; NOL6, nucleolar protein 6; NUP133, nucleoporin 133; PRDX3, peroxiredoxin 3; PRPF4B, pre-mRNA processing factor 4B; PSMA1, proteasome subunit alpha type-1; PYM1, PYM homolog 1, exon-junction-complex–associated factor; RBM39, RNA-binding motif protein 39; SENP2, SUMO1/sentrin/SMT3-specific peptidase 2; SIN3A, SIN3 transcription regulator family member A; SMNDC1, survival motor neuron domain containing 1; ST6GALNAC2, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4; SUMO1, small ubiquitin-like modifier 1; SUPT4H1, SPT4 homolog, DSIF elongation factor subunit; TBC1D8, TBC1 domain family member 8; THOC1, THO complex 1; TSPAN2, tetraspanin 2; U2AF1L4, splicing factor U2AF 26-kDa subunit; ZDHHC2, zinc finger DHHC-type containing 2.