Talboom‐Kamp 2016.

Trial name or title	e‐Vita: design of an innovative approach to COPD disease management in primary care through eHealth application
Methods	Prospective parallel cohort design using an interrupted time series (ITS) approach
Participants	Patients with chronic obstructive pulmonary disease (COPD) from general practices are eligible. Also, patients are eligible when they receive a diagnosis of COPD according to GOLD (Global Initiative for Chronic Obstructive Lung Disease) criteria (post‐bronchodilator forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC). Patients are excluded if they are unable to fill in questionnaires, have no access to the Internet, have a terminal illness, are immobile, or have severe substance abuse problems
Interventions	Web portal (e‐Vita) that provides continuous education and contact with healthcare professionals for people with COPD
Outcomes	Primary outcome is clinical and is expressed as health status, measured by the Clinical COPD Questionnaire (CCQ) Secondary outcomes include disability associated with breathlessness. This is measured using the Medical Research Council (MRC) breathlessness scale; quality of life (QoL) will be assessed using EuroQol‐5D (EQ‐5D) Adoption of the portal: Usage of the portal is monitored continuously by log files. User satisfaction is measured by purpose‐designed questionnaires Direct costs of the intervention and COPD care: Self‐efficacy is measured using the Generalized Self‐Efficacy Scale (GSES)
Starting date	Not reported
Contact information	E.Talboom@saltro.nl; 1 Public Health and Primary Care Department, LUMC, P.O. Box 9600, 2300 RC Leiden, The Netherlands, 2 SALTRO Diagnostic Centre, Mississippidreef 83, 3565 CE Utrecht, The Netherlands
Notes	Eligibility for our review is unclear from the protocol; will review findings paper