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. 2012 Aug 15;2012(8):CD005652. doi: 10.1002/14651858.CD005652.pub2

Summary of findings 6. Mentalisation‐Based Treatment‐outpatient (MBT‐out) versus treatment as usual (TAU) for people with borderline personality disorder.

MBT‐out compared to TAU for people with borderline personality disorder
Patient or population: patients with borderline personality disorder
Settings: outpatient
Intervention: MBT‐out
Comparison: TAU
Outcomes Illustrative comparative risks* (95% CI) Relative effect
(95% CI) No of Participants
(studies) Quality of the evidence
(GRADE) Comments
Assumed risk Corresponding risk
TAU MBT‐out
Suicidality
no. of participants with life‐threatening suicide attempts (last 6 months)
Follow‐up: mean 18 months 254 per 1000 28 per 1000
(8 to 117) RR 0.11 
(0.03 to 0.46) 134
(1 study) ⊕⊕⊕⊝
moderate1  
Parasuicidality
no. of participants with self‐harm incidents (last 6 months)
Follow‐up: mean 18 months 429 per 1000 240 per 1000
(146 to 394) RR 0.56 
(0.34 to 0.92) 134
(1 study) ⊕⊕⊕⊝
moderate1  
Interpersonal problems
IIP2
Follow‐up: mean 18 months The mean interpersonal problems score in the control groups was
1.65 points The mean interpersonal problems score in the intervention groups was
0.95 standard deviations lower
(1.30 to 0.59 lower)   134
(1 study) ⊕⊕⊕⊝
moderate1  
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: Confidence interval; RR: Risk ratio
GRADE Working Group grades of evidence
High quality: Further research is very unlikely to change our confidence in the estimate of effect.
Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very low quality: We are very uncertain about the estimate.

1Total sample size less than 400
2Inventory of interpersonal problems