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. 2012 Aug 15;2012(8):CD005652. doi: 10.1002/14651858.CD005652.pub2

Summary of findings 7. Transference‐Focused Psychotherapy (TFP) versus community treatment by experts (CTBE) for people with borderline personality disorder.

TFP compared to CTBE for people with borderline personality disorder
Patient or population: patients with borderline personality disorder
Settings: outpatient
Intervention: TFP
Comparison: CTBE
Outcomes Illustrative comparative risks* (95% CI) Relative effect
(95% CI) No of Participants
(studies) Quality of the evidence
(GRADE) Comments
Assumed risk Corresponding risk
CTBE TFP
BPD total severity
mean number of BPD criteria met. Scale from: 0 to 9.
Follow‐up: mean 12 months The mean BPD total severity score in the control groups was
5.63 criteria The mean BPD total severity score in the intervention groups was
0.55 standard deviations lower
(0.95 to 0.16 lower)   104
(1 study) ⊕⊕⊕⊝
moderate1  
Suicidality
no. of participants with suicidal act (last 12 months)
Follow‐up: mean 12 months 212 per 1000 135 per 1000
(57 to 319) RR 0.64 
(0.27 to 1.51) 104
(1 study) ⊕⊕⊕⊝
moderate1  
Parasuicidality
no. of participants with self‐harming behaviour (last 12 months)
Follow‐up: mean 12 months 673 per 1000 734 per 1000
(565 to 942) RR 1.09 
(0.84 to 1.40) 104
(1 study) ⊕⊕⊕⊝
moderate1  
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: Confidence interval; RR: Risk ratio
GRADE Working Group grades of evidence
High quality: Further research is very unlikely to change our confidence in the estimate of effect.
Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very low quality: We are very uncertain about the estimate.

1Total sample size less than 400