Summary of findings 16. Systems training for emotional predictability and problem solving for borderline personality disorder + individual therapy (STEPPS+IT) versus treatment as usual (TAU) for borderline personality disorder.
| STEPPS+IT compared to TAU for borderline personality disorder | ||||||
| Patient or population: patients with borderline personality disorder Settings: outpatient Intervention: STEPPS+IT Comparison: TAU | ||||||
| Outcomes | Illustrative comparative risks* (95% CI) | Relative effect (95% CI) | No of Participants (studies) | Quality of the evidence (GRADE) | Comments | |
| Assumed risk | Corresponding risk | |||||
| TAU | STEPPS+IT | |||||
| BPD total severity BPD‐401 Follow‐up: mean 4.5 months | The mean BPD total severity score in the control groups was 95.1 points | The mean BPDtotal severity score in the intervention groups was 0.55 standard deviations lower (1.11 lower to 0.00 higher) | 52 (1 study) | ⊕⊕⊝⊝ low2 | ||
| Impulsivity no. of participants scoring above BPDSI‐IV3 impulsivity cut‐off score Follow‐up: mean 4.5 months | 733 per 1000 | 682 per 1000 (484 to 946) | RR 0.93 (0.66 to 1.29) | 58 (1 study) | ⊕⊕⊝⊝ low2 | |
| Parasuicidality no. of participants scoring above BPDSI‐IV3 parasuicide cut‐off score Follow‐up: mean 4.5 months | 433 per 1000 | 572 per 1000 (338 to 962) | RR 1.32 (0.78 to 2.22) | 58 (1 study) | ⊕⊕⊝⊝ low2 | |
| Interpersonal problems WHOQOL‐BREF4‐social relationships (mean scores multiplied by ‐1) Follow‐up: mean 4.5 months | The mean interpersonal problems score in the control groups was ‐12.00 points | The mean interpersonal problems score in the intervention groups was 0.27 standard deviations lower (0.81 lower to 0.27 higher) | 53 (1 study) | ⊕⊕⊝⊝ low2 | ||
| *The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval; RR: Risk ratio; | ||||||
| GRADE Working Group grades of evidence High quality: Further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: We are very uncertain about the estimate. | ||||||
1Borderline Personality Disorder Checklist‐40 2Total sample size less than 100 3Borderline Personality Disorder Severity Index 4World Health Organization Quality of Life Assessment‐Bref