NTR2175.

Study name	Mentalisation‐Based Treatment versus care‐as‐usual in the treatment of severe borderline personality disorders
Methods	RCT
Participants	A severe BPD on the basis of standardised criteria for borderline personality disorder and assessed with the Dutch version of the Structured Clinical Interview for DSM‐III‐R (SCID‐II) (13), and the Borderline Personality Disorder Severity Index (BPDSI) (14). Patients must meet the criteria for borderline personality disorder as determined with the SCID‐II and have a total score on the BPDSI of at least 24, indicating a severe BPD. Patients with co‐morbid personality disorders will not be excluded.
Interventions	36 months of 1. MBT 2. TAU
Outcomes	Primary: frequency and severity of manifestations of BPD as measured with the BPDSI Secondary: 1. Number of suicide acts; 2. Self‐mutilation; 3. Depression; 4. Subjective experiences of symptoms; 5. Social and interpersonal functioning; 6. Personality functioning; 7. Quality of life; 8. Treatment adherence
Starting date	01 March 2010
Contact information	Prof Dr J Dekker, Viersprong Institute for Studies on Personality Disorders (BISPD), Department of Rehabilitation Medicine, VUmc PO Box 7057, 1007 MB, Amsterdam, NL; j.dekker@vumc.nl
Notes