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. Author manuscript; available in PMC: 2019 Oct 4.
Published in final edited form as: Cell. 2018 Sep 20;175(2):416–428.e13. doi: 10.1016/j.cell.2018.08.048

Figure 3:

Figure 3:

Recurrent cancer mutations have low MHC-II presentation in the TCGA population. (A) A violin plot denoting the distribution of PHBR-II presentation scores across all patients in TCGA for 6 different classes of residue. Tumor Suppressor is abbreviated as TS. Mutations observed >10 times in TCGA are displayed. (B) Cumulative distribution functions (CDF) for the 6 different classes of residue. (C) A violin plot with the distribution of somatic mutations occurring at different frequencies: passenger mutations in non-cancer implicated genes observed ≤2 in TCGA and mutations in cancer implicated genes observed 3-10 times, 11- 40 times and >40 times in TCGA. (D) CDFs for somatic mutations occurring at different frequencies. For both (A, C), the white dots represent the median, the thick dark grey lines denote the interquartile of the data and the thin dark grey lines denote the 1.5 IQR range. See also Figure S4 and Table S4.