Table 2.

Demographics and HbA1c of All Age Patients and >19 y of Age With Extreme Insulin Resistance at the Time of Thyroid Imaging

Parameter/Disease	All Patients			Patients <19 y of Age
	INSR Mutation (n = 11)	Lipodystrophy (n = 81)	P Value	INSR Mutation (n = 7)	Lipodystrophy (n = 23)	P Value
Age, ya	18.1 ± 10.6 (7–47)	30.9 ± 18 (1–79)	0.01	13.1 ± 3.9 (7–18)	13.2 ± 4.6 (2–18)	0.81
% Male	45	16	0.036	43	22	0.34
BSA, m2	1.34 ± 0.36	1.67 ± 0.3	0.006	1.28 ± 0.34	1.42 ± 0.4	0.33
BMI	21.2 ± 4.4	23.3 ± 5	0.2	19.3 ± 3.2	19.6 ± 4.7	0.8
% on Metreleptin	36	67	0.048	29	70	0.08
HbA1c, % (range)	8.5 ± 3.1 (4.8–13.3);	7.1 ± 2.1 (4.3–13.2);	0.2	8.2 ± 2 (5.3–10.8):	6.42 ± 2 (4.3–11);	0.04
	n = 11	n = 76		n = 7	n = 22

Boldface indicates statistically significant P value (P < 0.05).

^aAge is given as mean ± SD (range).