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. 2019 Jan 16;104(6):2216–2228. doi: 10.1210/jc.2018-02289

Table 6.

Thyroid Nodule Description in Lipodystrophy and INSR Mutation Groups

Parameters All Patients
Patients <19 y of Age
INSR Mutation Lipodystrophy INSR Mutation Lipodystrophy
N 11 80 7 23
Patients with nodules, n (%) 1 (9.1%) 29 (36.3%) 1 (14.3%) 4 (17.4%)
Number of nodules 1 55 1/1 4/4
Size, cm 0.9 0.86 ± 0.42 (0.3–2.7) 0.9 1.2; 1; 0.4; 0.4
Composition
 Solid 1 22 1 2
 Solid–cystic/spongiform 0 33 0 2
Echogenicity
 Hyperechoic 0 6 0 1
 Hypoechoic 0 33 0 3
 Very hypoechoic 1 12 1 0
 Isoechoic 0 4 0 0
Margins
 Smooth 0 41 0 4
 Ill-defined 1 12 1 0
 Lobulated/irregular 0 2 0 0
 Extrathyroidal extension 0 0 0 0
Foci (calcifications)
 None 0 15 0 4
 Microcalcifications 1 40 1 0
 Macrocalcifications 0 2 0 0
 Rim/peripheral 0 15 0 0