Table 6.
Thyroid Nodule Description in Lipodystrophy and INSR Mutation Groups
Parameters | All Patients |
Patients <19 y of Age |
||
---|---|---|---|---|
INSR Mutation | Lipodystrophy | INSR Mutation | Lipodystrophy | |
N | 11 | 80 | 7 | 23 |
Patients with nodules, n (%) | 1 (9.1%) | 29 (36.3%) | 1 (14.3%) | 4 (17.4%) |
Number of nodules | 1 | 55 | 1/1 | 4/4 |
Size, cm | 0.9 | 0.86 ± 0.42 (0.3–2.7) | 0.9 | 1.2; 1; 0.4; 0.4 |
Composition | ||||
Solid | 1 | 22 | 1 | 2 |
Solid–cystic/spongiform | 0 | 33 | 0 | 2 |
Echogenicity | ||||
Hyperechoic | 0 | 6 | 0 | 1 |
Hypoechoic | 0 | 33 | 0 | 3 |
Very hypoechoic | 1 | 12 | 1 | 0 |
Isoechoic | 0 | 4 | 0 | 0 |
Margins | ||||
Smooth | 0 | 41 | 0 | 4 |
Ill-defined | 1 | 12 | 1 | 0 |
Lobulated/irregular | 0 | 2 | 0 | 0 |
Extrathyroidal extension | 0 | 0 | 0 | 0 |
Foci (calcifications) | ||||
None | 0 | 15 | 0 | 4 |
Microcalcifications | 1 | 40 | 1 | 0 |
Macrocalcifications | 0 | 2 | 0 | 0 |
Rim/peripheral | 0 | 15 | 0 | 0 |