Table 6.
Thyroid Nodule Description in Lipodystrophy and INSR Mutation Groups
| Parameters | All Patients |
Patients <19 y of Age |
||
|---|---|---|---|---|
| INSR Mutation | Lipodystrophy | INSR Mutation | Lipodystrophy | |
| N | 11 | 80 | 7 | 23 |
| Patients with nodules, n (%) | 1 (9.1%) | 29 (36.3%) | 1 (14.3%) | 4 (17.4%) |
| Number of nodules | 1 | 55 | 1/1 | 4/4 |
| Size, cm | 0.9 | 0.86 ± 0.42 (0.3–2.7) | 0.9 | 1.2; 1; 0.4; 0.4 |
| Composition | ||||
| Solid | 1 | 22 | 1 | 2 |
| Solid–cystic/spongiform | 0 | 33 | 0 | 2 |
| Echogenicity | ||||
| Hyperechoic | 0 | 6 | 0 | 1 |
| Hypoechoic | 0 | 33 | 0 | 3 |
| Very hypoechoic | 1 | 12 | 1 | 0 |
| Isoechoic | 0 | 4 | 0 | 0 |
| Margins | ||||
| Smooth | 0 | 41 | 0 | 4 |
| Ill-defined | 1 | 12 | 1 | 0 |
| Lobulated/irregular | 0 | 2 | 0 | 0 |
| Extrathyroidal extension | 0 | 0 | 0 | 0 |
| Foci (calcifications) | ||||
| None | 0 | 15 | 0 | 4 |
| Microcalcifications | 1 | 40 | 1 | 0 |
| Macrocalcifications | 0 | 2 | 0 | 0 |
| Rim/peripheral | 0 | 15 | 0 | 0 |