Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Thyroid Phenotypes and Growth Factors in Patients With Extreme Insulin Resistance
| INSR, Homozygous | INSR, Heterozygous | Lipodystrophy | |
|---|---|---|---|
| Insulin resistance | Nonselective | Nonselective | Selective |
| IGF-1 | ↓ | Normal | Normal |
| Fasting insulin | ↑↑↑ | ↑↑ | ↑ |
| Thyroid functional status | Euthyroid | Euthyroid | Euthyroid |
| Thyroid size | Enlarged | Normal | Normal |
| Risk for thyroid nodules | Probably increased | Probably increased | Probably increased |
| Risk of thyroid cancer | Unknown | Unknown | Unknown |
