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High intrinsic aerobic capacity protects against acute (3-d) HFD-induced decreases in insulin sensitivity. (A) GIR was determined during HEC. (B) Plasma glucose and (C) plasma insulin were determined during the last 40 min of the HEC. Values are expressed as means ± SEM (n = 5 to 7). *P < 0.05 for main effect in HCR rats vs LCR rats; ††P < 0.05 for LFD vs HFD within strain.
