. 2019 Apr 10;160(5):1179–1192. doi: 10.1210/en.2019-00118

Table 1.

Animal Characteristics

	HCR		LCR
	LFD	HFD	LFD	HFD
Anthropometrics
Body weight, g	396.8 ± 8.1	402.9 ± 7.3	505.4 ± 17.1^a	498.2 ± 17.0^a
3-d Weight gain, g	7.2 ± 1.7	7.7 ± 1.8	5.3 ± 1.1	14.4 ± 1.2^b^,^c
3-d Food intake, g	15.6 ± 0.9	14.5 ± 0.9	15.4 ± 1.0	15.2 ± 0.8
3-d EI, kcal	59.9 ± 3.4	68.4 ± 4.2^d	57.3 ± 3.4	71.2 ± 4.0^d
3-d EI per body weight, kcal/g	150.0 ± 6.8	168.4 ± 9.3^d	117.3 ± 6.0^a	144.6 ± 6.8^a^,^d
Adipose tissue per body weight, mg/g
Epididymal	13.97 ± 0.75	14.04 ± 1.29	21.91 ± 1.00^a	24.33 ± 1.07^a
Retroperitoneal	14.04 ± 1.10	16.10 ± 1.20	26.82 ± 2.08^a	29.57 ± 1.84^a
Omental	2.77 ± 0.34	3.15 ± 0.30	4.46 ± 0.33^a	4.07 ± 0.29^a
Fasting plasma
Glucose, mg/dL	128.8 ± 6.5	132.6 ± 4.0	130.4 ± 4.2	144.1 ± 4.3^c
Insulin, ng/mL	2.95 ± 0.60	2.98 ± 0.39	3.46 ± 0.48	4.52 ± 0.80

Final body weight and weight gain after 3 d of an HFD are expressed as means ± SEM (n = 10 to 15). Three-day food intake, EI, and EI per body weight are expressed as means ± SEM (n = 10 to 15). Fat pad mass per body weight is expressed as means ± SEM (n = 10 to 14). Fasting plasma glucose and insulin following 3 d of an HFD are expressed as means ± SEM (n = 5 to 7).

^{^a}

P < 0.05 for main effect HCR vs LCR rats.

^{^b}

P < 0.05 for HCR vs LCR rats within diet.

^{^c}

P < 0.05 for LFD vs HFD within strain.

^{^d}

P < 0.05 for main effect of LFD vs HFD.