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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: J Neuroendocrinol. 2019 Mar 13;31(4):e12698. doi: 10.1111/jne.12698

FIGURE 1. Variation of estradiol levels by pubertal stage, sex and age.

FIGURE 1.

Because of concerns concerning the unreliability of the ELISA assay at the lower limit of detection (LOD; 1*10^−5 ug/d), none of the LOD samples was included in our analyses. The minimum estradiol level in our restricted sample was 2.13 ug/dL, with the bulk of estradiol values between 5–20 ug/dL, for both boys and girls. Mean age per pubertal stage are indicated on the scale at the bottom of the figure. Most children matured from pubertal stages 1–3 between ages 10–15 years old and from pubertal stages 3–4 between 15–20 years old. For interpretation of the references to color in this figure legend, the reader is referred to the web version of the article.