Table 1:

Number of base pair effect per allele included in the analysis based on data by the ENGAGE Consortium.[13]

SNP	Chromosome	Gene	Effect allele	Base Pairs*	EAF cases (%)	EAF controls (%)	Allelic OR	95%-CI	P-value**
rs11125529	2	ACYP2	A	66.9	12.7	13.3	0.95	0.82–1.10	0.49
rs10936599	3	TERC	C	117.3	24.4	22.2	1.14	1.01–1.28	0.02
rs7675998	4	NAF1	G	89.7	21.7	21.7	1.00	0.89–1.13	0.94
rs2736100	5	TERT	C	94.2	52.3	49.0	1.13	1.03–1.25	0.01
rs9420907	10	OBFC1	C	82.8	16.7	14.1	1.22	1.07–1.39	0.003***
rs3027234	17	CTC1	C	25.2	21.7	22.3	0.97	0.86–1.08	0.55
rs8105767	19	ZNF208	G	57.6	30.4	28.7	1.08	0.97–1.20	0.15
rs755017	20	RTEL1	G	74.1	13.5	12.1	1.15	1.00–1.33	0.05

^*Number of base pairs the affected allele increases the genotypically-estimated leukocyte telomere length (LTL)[13, 32]

^**p-value for risk for meningioma under an additive frequentist model

^***Significant after correction for multiple testing (eight degrees of freedom).

Abbreviations: EAF: estimated allele frequency; bp: base pairs, OR: odds ratio, LTL: Leukocyte telomere length.