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. Author manuscript; available in PMC: 2020 May 15.
Published in final edited form as: Eur J Pharm Sci. 2019 Mar 28;133:86–94. doi: 10.1016/j.ejps.2019.03.020

Fig. 1. NMS-873 inhibits both influenza A and B viruses.

Fig. 1.

(A) Chemical structure of NMS-873. (B) Cellular cytotoxicity of NMS-873 in MDCK cells. (C) Antiviral activity of NMS-873 against representative influenza A and B viruses. The antiviral activity of NMS-873 was determined in plaque reduction assay. Monolayers of MDCK cells overexpressing ST6Gal I were infected with indicated viruses and incubated with overlays containing a serial of concentrations of NMS-873, 1 μM of amantadine or 0.2 μM of oseltamivir carboxylate.