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. 2019 Apr 18;9:298. doi: 10.3389/fonc.2019.00298

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Copyright © 2019 Li, Song, Liu, Li, Huang, Su, Mao, Wang, Mo and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of miR-214 on irradiation-induced apoptosis in osteosarcoma. (A) Apoptotic analysis in scramble- or anti-miR-214-transfected U2OS cells with and without irradiation. Cells in the right quadrant represent early (lower right) and late (upper right) apoptotic cells, respectively. (B) Quantification of apoptotic ratio of the indicated groups. (C) Western blot analysis for cleaved caspase-3, cleaved caspase-9, cleaved PARP, and GAPDH (for protein normalization) was performed in scramble- or anti-miR-214-transfected U2OS cells without and with irradiation. Data are presented as mean ± SD of three independent experiments. ^*P < 0.05.