Table 1.
Correlation between miR-214 expression and clinicopathologic features of patients with osteosarcoma.
Parameters | Total | No. of patients† | Fisher exact test | |
---|---|---|---|---|
High miR-214 | Low miR-214 | P-value | ||
Gender | 0.442 | |||
Male | 20 | 12 | 8 | |
Female | 10 | 4 | 6 | |
Age | 0.713 | |||
≤ 16.5 | 17 | 10 | 7 | |
>16.5 | 13 | 6 | 7 | |
Histology | 0.769 | |||
Osteoblastic | 19 | 9 | 10 | |
Chondroblastic | 6 | 4 | 2 | |
Fibroblastic | 5 | 3 | 2 | |
Differentiation | 0.292 | |||
Well differentiation | 5 | 4 | 1 | |
Moderately differentiation | 12 | 4 | 8 | |
Poorly differentiation | 11 | 7 | 4 | |
Other | 2 | 1 | 1 | |
Location of Primary Tumor | ||||
Femur | 16 | 10 | 6 | 0.494 |
Tibia | 11 | 5 | 6 | |
Other | 3 | 1 | 2 | |
Lung metastasis | 0.026* | |||
Present | 16 | 12 | 4 | |
Absent | 14 | 4 | 10 |
P < 0.05 vs. lung metastasis absent.
The median expression of miR-214 in osteosarcoma tissues was used as a cutoff to divide samples into high or low subgroup.