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. 2019 Apr 18;9:298. doi: 10.3389/fonc.2019.00298

Table 1.

Correlation between miR-214 expression and clinicopathologic features of patients with osteosarcoma.

Parameters Total No. of patients Fisher exact test
High miR-214 Low miR-214 P-value
Gender 0.442
    Male 20 12 8
    Female 10 4 6
Age 0.713
     ≤ 16.5 17 10 7
    >16.5 13 6 7
Histology 0.769
    Osteoblastic 19 9 10
    Chondroblastic 6 4 2
    Fibroblastic 5 3 2
Differentiation 0.292
    Well differentiation 5 4 1
    Moderately differentiation 12 4 8
    Poorly differentiation 11 7 4
    Other 2 1 1
Location of Primary Tumor
    Femur 16 10 6 0.494
    Tibia 11 5 6
    Other 3 1 2
Lung metastasis 0.026*
    Present 16 12 4
    Absent 14 4 10
*

P < 0.05 vs. lung metastasis absent.

The median expression of miR-214 in osteosarcoma tissues was used as a cutoff to divide samples into high or low subgroup.