Table 1.
The potential role of CD8+ T cells in different autoimmune diseases.
| Diseases | Level of CD8+ T cells | Potential role of CD8+ T cells | References |
|---|---|---|---|
| GD | Decreased | Causes the production of intrathyroidal autoantibodies | (110, 111) |
| MS | Increased | Mediates inflammation | (112) |
| SSc | Increased | Contributes to the skin fibrosis | (113, 114) |
| T1D | Increased | Induces β-cell death | (115) |
| SLE | Increased | Induces autoantibody appearance and causing organ damage | (116, 117) |
| SAA | Increased | Causes hematopoietic cell health | (118) |
| Vitiligo | Increased | Mediates the destruction of melanocytes | (119) |