Table 3.
Comparison of gene expression in treated and regrown B. burgdorferi versus treated only.
| Gene ID | Gene product description | Base mean | log2 fold change | lfcSE | Stat | p-value | padj |
|---|---|---|---|---|---|---|---|
| Up-regulated in regrown versus treated | |||||||
| BB_A03 | Outer membrane protein | 572.4995 | 2.883544 | 0.5903 | -4.88488 | 1.03E-06 | 0.000923 |
| BB_A74 | Osm28 a periplasmic protein associated with the outer membrane | 8531.673 | 2.880761 | 0.625713 | -4.60397 | 4.15E-06 | 0.001071 |
| BB_I39 | Surface antigen | 286.618 | 2.734333 | 0.58228 | -4.69591 | 2.65E-06 | 0.000923 |
| BB_J09 | Outer surface protein D | 2587.885 | 2.638443 | 0.579187 | -4.55542 | 5.23E-06 | 0.001071 |
| BB_J41 | Antigen P35 | 293.9898 | 2.607348 | 0.576747 | -4.52079 | 6.16E-06 | 0.001071 |
| BB_J10 | Pseudo | 65.80785 | 2.527191 | 0.618168 | -4.08819 | 4.35E-05 | 0.006478 |
| BB_A62 | 6.6 kDa outer membrane lipoprotein associated with tick phase and tick to mammal transmission | 3028.1 | 2.505728 | 0.53339 | -4.69774 | 2.63E-06 | 0.000923 |
| BB_A55 | Hypothetical protein; pseudo | 91.59374 | 2.364567 | 0.596799 | -3.96208 | 7.43E-05 | 0.00861 |
| BB_0614 | Hypothetical protein | 321.2092 | 2.284102 | 0.613485 | -3.72316 | 0.000197 | 0.018655 |
| BB_D18 | Hypothetical protein | 223.7287 | 2.249952 | 0.559689 | -4.02 | 5.82E-05 | 0.007588 |
| BB_A69 | Putative surface protein | 568.7318 | 2.18589 | 0.60856 | -3.59191 | 0.000328 | 0.026337 |
| BB_A68 | cspA; complement regulator-acquiring surface protein 1 | 521.7471 | 2.077714 | 0.548417 | -3.78856 | 0.000152 | 0.015804 |
| BB_A59 | Hypothetical protein | 1452.77 | 2.056081 | 0.566537 | -3.62921 | 0.000284 | 0.02471 |
| BB_A15 | Outer-surface protein A (OspA) | 10027.5 | 2.016905 | 0.60385 | -3.34008 | 0.000838 | 0.054598 |
| BB_0839 | Hypothetical protein | 66.6184 | 2.004598 | 0.587771 | -3.41051 | 0.000648 | 0.045087 |
| BB_0335 | Peptide ABC transporter ATP-binding protein (OppF) | 133.4096 | 1.94966 | 0.550044 | -3.54455 | 0.000393 | 0.029299 |
| BB_0334 | Peptide ABC transporter ATP-binding protein (OppD) | 174.8033 | 1.828725 | 0.554848 | -3.2959 | 0.000981 | 0.060191 |
| Down-regulated in Regrown versus Treated | |||||||
| BB_P42 | Phage terminase large subunit | 90.95504 | -2.00516 | 0.637717 | 3.144283 | 0.001665 | 0.096474 |