Table 1.
Patients' clinical information.
| Target/whole exom sequence | Total | |||||
|---|---|---|---|---|---|---|
| Clinical | AAH | AIS | MIA | AD | GGNs | |
| Sample# | 25/0 | 13/9 | 5/5 | 8/4 | 69 | |
| Sample type | FFPE | 25/0 | 13/0 | 5/0 | 8/0 | 51 |
| Frozen | 0/0 | 0/9 | 0/5 | 0/4 | 18 | |
| Control tissue | lymph node | 25/0 | 13/0 | 5/0 | 8/0 | 51 |
| adjacent lung | 0/0 | 0/9 | 0/5 | 0/4 | 18 | |
| Stage | T1N0M0 | 25/0 | 13/9 | 5/5 | 8/4 | 69 |
| Size(cm) | <0.5 | 7/0 | 0/3 | 0/0 | 0/0 | 10 |
| 0.5–1 | 18/0 | 13/6 | 5/5 | 1/4 | 52 | |
| 1–2.5 | 0/0 | 0/0 | 0/0 | 7/0 | 7 | |
| Age (years) | <60 | 12/0 | 6/3 | 3/3 | 4/0 | 31 |
| ≥60 | 13/0 | 7/6 | 2/2 | 4/4 | 38 | |
| Gender | Male | 7/0 | 3/2 | 0/1 | 4/0 | 17 |
| Female | 18/0 | 10/7 | 5/4 | 4/4 | 52 | |
| Smoking | Yes | 0/0 | 0/2 | 0/1 | 0/0 | 3 |
| No | 25/0 | 13/7 | 5/4 | 8/4 | 66 | |
| Follow-up (year) | <2 | 0/0 | 0/0 | 0/0 | 0/0 | 0 |
| >2 | 25/0 | 13/9 | 5/5 | 8/4 | 69 | |
| Disease-free | Yes | 25/0 | 13/9 | 5/5 | 8/4 | 69 |
Atypical adenomatous hyperplasia (AAH), Adenocarcinoma in situ (AIS), Minimally invasive adenocarcinoma (MIA), Invasive adenocarcinoma (AD), and Ground-glass nodules (GGNs).