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. 2019 Apr 24;9:6494. doi: 10.1038/s41598-019-42846-y

Table 2.

Concordance between qPCR and Fluidigm for the detection of pneumococcal serotypes in PCV-vaccinated, HIV-uninfected children.

Serotype qPCR Fluidigm P-value Concordance (kappa) Sensitivity (%) Specificity (%)
LytA 244(72.8) 246(73.4) 0.16 0.98 98.8 100
1 3(0.9) 5(1.5) 0.16 0.75 95 100
3 1(0.3) 1(0.3) 1 100 100
4 3(0.9) 4(1.2) 0.32 0.86 80 100
5 13(3.9) 13(3.9) 1 100 100
6A/B 31 (9.3) 31 (9.3) 1 100 100
6C/D 2(0.6) 2(0.6) 1 100 100
7C 8(2.4) 6(1.8) 0.16 0.85 100 99.3
9A/L/N/V 8(2.4) 8(2.4) 1 100 100
10A 5(1.5) 6(1.8) 0.32 0.91 83.3 100
11A/B/C/D/F 9(2.7) 9(2.7) 1 100 100
12ABF/44/46 5(1.5) 5(1.5) 1 100 100
13 6(1.8) 6(1.8) 1 100 100
14 7(2.1) 7(2.1) 1 100 100
15A/B/C/F 14(4.2) 14(4.2) 1 100 100
16F 9(2.7) 9(2.7) 1 100 100
17F 6(1.8) 6(1.8) 1 100 100
18A/B/C 6(1.8) 7(2.1) 0.32 0.93 85.7 100
19A 36(10.7) 36(10.7) 1 100 100
19B/F 48(14.3) 50(14.9) 0.08 0.96 94 100
20 1(0.3) 1(0.3) 1 100 100
21 5(1.5) 5(1.5) 1 100 100
23A/B 8(2.4) 8(2.4) 1 100 100
23F 15(4.5) 15(4.5) 1 100 100
34/37/17F 13(3.9) 13(3.9) 1 100 100