Table 5.
Plasma and liver alanine transaminase (ALT), aspartate transaminase (AST),acid phosphatase (AcP), alkaline phosphatase (AlP), gama-glutamyl transferase (GGT) and lactate dehydrogenase(LDH) of male rats treated with aluminum oxide nanoparticles, zinc oxide nanoparticles and their combination.
| Parameter | Experimental groups |
|||
|---|---|---|---|---|
| Control | Al2O3NPs | ZnONPs | Combination | |
| Plasma | ||||
| ALT (U/L) | 64 ± 1.8 c | 104 ± 1.8 b | 108 ± 2.1 b | 169 ± 2.4 a |
| AST (U/L) | 58 ± 1.1 c | 97 ± 1.5 b | 97 ± 1.8 b | 125 ± 1.8 a |
| AcP (U/L) | 14.3 ± 0.3 d | 18.5 ± 0.3 c | 19.3 ± 0.3 b | 23.2 ± 0.6 a |
| AlP (U/L) | 134 ± 3.41c | 183 ± 1.98 b | 180 ± 2.84 b | 210 ± 2.86 a |
| GGT (U/L) | 17.6 ± 1.24 d | 45.8 ± 1.38 c | 54.9 ± 1.44 b | 75.2 ± 1.24 a |
| LDH (U/L) | 1098 ± 24.7 c | 1307 ± 22.2 b | 1306 ± 20.9 b | 1488 ± 29.8 a |
| Liver | ||||
| ALT (U/mg) | 391 ± 5.4 a | 292 ± 5.8 b | 287 ± 5.5 b | 223 ± 4.6 c |
| AST (U/mg) | 216 ± 3.04 a | 164 ± 3.04 b | 160 ± 3.25 b | 118 ± 2.31 c |
| AcP (U/mg) | 19.8 ± 0.36 a | 11.8 ± 0.61 b | 11.1 ± 0.94 c | 9.6 ± 0.45 d |
| AlP (U/mg) | 202 ± 2.51 a | 139 ± 2.36 b | 133 ± 2.55 b | 82 ± 2.35 c |
| GGT (U/mg) | 28.3 ± 0.84 a | 15.6 ± 0.59b | 14.0 ± 0.36 c | 9.0 ± 0.43 d |
| LDH (U/mg) | 964 ± 9.3 a | 742 ± 9.8 b | 726 ± 12.1 b | 571 ± 10.6 c |
Data presented as Mean±SE. For each parameter, the groups with different superscript letters are significantly differ, p < 0.05.