1 FEV1 (% predicted) |
4 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
1.1 <= 12 weeks |
1 |
12 |
Mean Difference (IV, Fixed, 95% CI) |
11.40 [0.85, 21.95] |
1.2 > 12 weeks |
3 |
118 |
Mean Difference (IV, Fixed, 95% CI) |
3.83 [‐1.37, 9.04] |
2 Morning PEF (L/min) |
2 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
2.1 < =12 weeks |
1 |
12 |
Mean Difference (IV, Fixed, 95% CI) |
‐75.0 [‐228.70, 78.70] |
2.2 >12 weeks |
1 |
51 |
Mean Difference (IV, Fixed, 95% CI) |
10.0 [‐14.39, 34.39] |
3 Morning PEF (L/min) change from baseline |
5 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
3.1 < =12 weeks |
3 |
320 |
Mean Difference (IV, Fixed, 95% CI) |
2.93 [‐10.07, 15.93] |
3.2 >12 weeks |
2 |
797 |
Mean Difference (IV, Fixed, 95% CI) |
7.00 [‐1.80, 15.79] |
4 Diary Card Symptom Score (day) change baseline |
2 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
4.1 < = 12 weeks |
2 |
794 |
Mean Difference (IV, Fixed, 95% CI) |
0.02 [‐0.06, 0.11] |
4.2 > 12 weeks |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
5 Diary Card Symptom Score (night) change from baseline |
2 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
5.1 < = 12 weeks |
2 |
800 |
Mean Difference (IV, Fixed, 95% CI) |
0.02 [‐0.06, 0.10] |
5.2 >12 weeks |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
6 Rescue Medications (puffs per day) change from baseline |
2 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
6.1 < = 12 weeks |
2 |
788 |
Mean Difference (IV, Fixed, 95% CI) |
‐0.11 [‐0.39, 0.17] |
6.2 >12 weeks |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
7 Rescue Medications (puffs per night) change from baseline |
2 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
7.1 < = 12 weeks |
2 |
788 |
Mean Difference (IV, Fixed, 95% CI) |
‐0.03 [‐0.12, 0.05] |
7.2 >12 weeks |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
8 Withdrawal Due to Adverse Event |
2 |
|
Risk Ratio (M‐H, Fixed, 95% CI) |
Subtotals only |
8.1 < = 12 weeks |
2 |
301 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.59 [0.14, 2.43] |
8.2 > 12 weeks |
0 |
0 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |