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. 2019 Mar 7;10(4):517–527. doi: 10.1039/c9md00051h

Table 2. Synergy evaluation with 8 μg mL–1 peptide–levofloxacin conjugates 1–12 in combination with fluoroquinolones (FQ) against wild-type P. aeruginosa PAO1.

Conjugate MIC (μg ml–1) of FQs in combination with 8 μg ml–1 conjugates
Ciprofloxacin Levofloxacin Moxifloxacin
1 0.125 0.500 1
2 0.125 0.250 1
3 0.125 0.250 1
4 0.063 0.250 1
5 0.125 0.500 1
6 0.125 0.500 1
7 0.125 0.250 1
8 0.063 0.250 1
9 0.063 0.250 1
10 0.031 0.063 0.250
11 0.031 0.125 0.250
12 0.031 0.125 0.250
Antibiotic alone: 0.125 0.500 1