Table 2. Synergy evaluation with 8 μg mL–1 peptide–levofloxacin conjugates 1–12 in combination with fluoroquinolones (FQ) against wild-type P. aeruginosa PAO1.
| Conjugate | MIC (μg ml–1) of FQs in combination with 8 μg ml–1 conjugates |
||
| Ciprofloxacin | Levofloxacin | Moxifloxacin | |
| 1 | 0.125 | 0.500 | 1 |
| 2 | 0.125 | 0.250 | 1 |
| 3 | 0.125 | 0.250 | 1 |
| 4 | 0.063 | 0.250 | 1 |
| 5 | 0.125 | 0.500 | 1 |
| 6 | 0.125 | 0.500 | 1 |
| 7 | 0.125 | 0.250 | 1 |
| 8 | 0.063 | 0.250 | 1 |
| 9 | 0.063 | 0.250 | 1 |
| 10 | 0.031 | 0.063 | 0.250 |
| 11 | 0.031 | 0.125 | 0.250 |
| 12 | 0.031 | 0.125 | 0.250 |
| Antibiotic alone: | 0.125 | 0.500 | 1 |