Table 1.

Application of TCM Preparations in the treatment of acute kidney injury.

Names	Origins	Models	Function	Mechanisms
A&A	Astragalus membranaceus var. mongholicus and Angelica sinensis	I/R-induced kidney injury	Decreasing cell necrosis	By inducing JNK (Cai et al., 2001; Meng et al., 2007)
DFD	Radix et Rhizoma Rhei, Radix Aconiti Lateralis Praeparata, and Radix et Rhizoma Asari	Adenine-induced renal injury	Inhibiting apoptosis	By blocking TGF-β1-JNK (Tu et al., 2014)
Xuebijing injection	Radix paeoniae rubra, Chuan dome, Salvia miltiorrhiza, Safflower, and Chinese angelica	Serious scald-induced renal injury	Alleviating renal function	By suppressing HMGB1 (Wang et al., 2007)
HLJDD	Rhizoma coptidis (RC), Cortex phellodendri (CP), Radix scutellariae (RS), and Fructus gardenia	LPS-induced AKI	Attenuating apoptosis	Activating the Akt/HO-1 pathway and inhibiting NF-kB and MAPK activation (Li et al., 2017)
ZDW	Cornus officinalis Siebold & Zucc., Radix Rehmanniae preparata, Dioscorea oppositifolia L., Cortex Phellodendri, rhizome, Moutan Cortex, Rhizoma Alismatis, and Wolf	Gentamicin-induced renal injury	Attenuating apoptosis	By limiting caspase-3 activation (Hsu et al., 2014)