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. 2019 Apr 12;58(16):2160–2166. doi: 10.1021/acs.biochem.8b01208

Figure 1.

Figure 1

Ectopically expressed olfactory receptor (exOR) sensors and the chemical panel. (A) OR deorphanization workflow. (B) Yeast-based OR sensor. OR (blue) is expressed in a yeast sensor strain that links receptor activation to green fluorescent protein (GFP). (C) Principle component analysis of the 57-member chemical panel. Chemical Spaces (CS): CS1, red dot; CS2, green dot; CS3, blue dot; CS4, orange dot; CS5, purple square; CS6, light blue square; CS7, pink dot; CS8, black square. (D) Localization of human ORs when expressed in yeast.