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. 2019 Apr 12;58(16):2160–2166. doi: 10.1021/acs.biochem.8b01208

Figure 3.

Figure 3

Confirming OR-dependent activation with validated chemicals. Dose–response curves of validated chemicals in the presence (solid lines) and absence (dotted lines) of ORs: (A) OR2A7 and OR2T4 with α-pinene, (B) OR2A7, OR2T4, and OR10S1 with lilial, (C) OR51B5, OR2T4, and OR2A42 with farnesol, and (D) OR2T4 and OR10S1 with undecanal and nonanal, respectively. All measurements were carried out in triplicate, and means ± the standard deviation are shown. Figure S3 shows dose–response curves of three OR/chemical pairs that do not show OR-dependent GFP expression. Table S8 lists R2 values for dose–response fits.