Confirming OR-dependent activation with
validated chemicals. Dose–response
curves of validated chemicals in the presence (solid lines) and absence
(dotted lines) of ORs: (A) OR2A7 and OR2T4 with α-pinene, (B)
OR2A7, OR2T4, and OR10S1 with lilial, (C) OR51B5, OR2T4, and OR2A42
with farnesol, and (D) OR2T4 and OR10S1 with undecanal and nonanal,
respectively. All measurements were carried out in triplicate, and
means ± the standard deviation are shown. Figure S3 shows dose–response curves of three OR/chemical
pairs that do not show OR-dependent GFP expression. Table S8 lists R2 values for dose–response
fits.