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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Cornea. 2019 May;38(5):658–661. doi: 10.1097/ICO.0000000000001865

TABLE 1.

Extraglandular Ocular Complications of Sjögren Syndrome

Type of Complication Cumulative Incidence (or No. Cases) References Study Design
Conjunctival inflammation
 Papillary conjunctivitis 1.4% of 163 patients Akpek et al,17 2015 Cohort study
 Follicular conjunctivitis 1.4% of 163 patients Akpek et al,17 2015 Cohort study
 Cicatrizing conjunctivitis 1.4% of 163 patients Akpek et al,17 2015 Cohort study
Corneal inflammation
 Haze/scarring 1.4% of 163 patients Akpek et al,17 2015 Cohort study
 Sterile corneal ulcer/infiltration 0.7% of 163 patients Akpek et al,17 2015 Cohort study
 Corneal melt/perforation 1.4% of 163 patients Akpek et al,17 2015 Cohort study
5 cases Gottsch,29 2000 Case series
2 cases Cohen,28 1982 Case series
2 cases Shan,32 2009 Case series
1 case Murtagh,30 2018 Case study
1 case Ou,31 2007 Case study
1 case Vivino,33 2001 Case study
Other inflammation
 Uveitis 2.0% of 163 patients Akpek et al,17 2015 Cohort study
8 cases Rosenbaum,35 1987 Case series
1 case Bridges,34 1992 Case report
 Scleritis/episcleritis 2.0% of 163 patients Akpek et al,17 2015 Cohort study
1 case Ahmadi-Simab,36 2005 Case study
1 case Bamrolia,37 2012 Case study
1 case Choi,38 2012 Case study
 Optic neuritis 2.0% of 163 patients Akpek et al,17 2015 Cohort study
 Retinal vasculitis 0.7% of 163 patients Akpek et al,17 2015 Cohort study