Table 4.
Top biological functions of DEGs within pituitary glands of HG and LG chickens
| aTop Biological Function | bDEGs (#) | cP-Value |
|---|---|---|
| Molecular and cellular function | ||
| Cell death | 46 | 9.96E-05 – 2.25E-02 |
| Cell cycle | 19 | 1.27E-04 – 2.25E-02 |
| Cell-to-cell signaling and interaction | 26 | 6.86E-04 – 2.25E-02 |
| Cellular compromise | 6 | 3.87E-04 – 2.09E-02 |
| Cellular growth and proliferation | 46 | 1.24E-03 – 2.20E-02 |
| Physiological system development and function | ||
| Cardiovascular system development and function | 16 | 5.36E-05 – 2.25E-02 |
| Organ morphology | 12 | 5.36E-05 – 1.13E-02 |
| Hematological system development and function | 32 | 1.16E-04 – 2.05E-02 |
| Tissue morphology | 24 | 1.16E-04 – 2.05E-02 |
| Endocrine system development and function | 6 | 7.13E-04 – 2.25E-02 |
aAs determined by Ingenuity Pathway Analysis (IPA) biological function prediction
bThe number of differentially expressed genes between HG and LG birds from our dataset contained within each category
cP-values were determined by IPA software based on the number of DEGs from the dataset within each biological category divided by the total number of known genes assigned to that category within the database