Table 1.

BA profile for individual species

	Average Intrahepatic BA Pool, % (n ≥ 8)				P Values for Direct Comparisons (t-test)
Bile Acid Species	CC	HC	CH	HH	CC versus HC	CH versus HH	CC versus CH	HC versus HH
MCA	24.5	29.5	37	25.5	0.02*	0.18	0.19	0.01*
TMCA	12	9.5	9	9.5	0.57	0.95	0.64	0.96
UDCA	1.5	1.5	1.5	1.5	0.99	0.80	0.53	0.57
TUDCA	1	0.5	1	1	0.56	0.39	0.19	0.93
GCA	<0.5	<0.5	<0.5	<0.5	0.18	0.74	0.68	0.79
TCA	46.5	47.5	42	50	0.12	0.54	0.77	0.02*
CA	5.5	4.5	6	5.5	0.52	0.49	0.45	0.67
TCDCA	2	3	1.5	2.5	0.07	0.85	0.02*	<0.01*
TDCA	5.5	2.5	1	3.5	<0.01*	0.18	<0.01*	0.01*
TLCA	<0.5	<0.5	<0.5	<0.5	0.01*	0.76	0.97	<0.01*
LCA	<0.5	<0.5	<0.5	<0.5	0.20	0.63	0.32	0.03*
CDCA	1.09	1.5	0.5	1	0.07	0.67	0.49	0.02*
DCA	0.25	<0.5	<0.5	0.5	0.01*	0.14	0.09	0.03*
GCDCA	<0.5	<0.5	<0.5	<0.5	0.60	0.28	0.53	0.95
GDCA	<0.5	<0.5	<0.5	<0.5	0.02*	0.70	0.02*	0.44

Data show average percent of total intrahepatic bile acid (BA) pool for each individual species and P values for t-test comparing individual BA percentages between groups with comparison noted. CC, maternal control (CON)-offspring chow; HC, maternal high-fat/high-sucrose (HF/HS)-offspring chow; CH, maternal CON-offspring high-transfat, cholesterol, fructose (HTFC); HH, maternal HF/HS-offspring HTFC. n ≥ 8 in each group.

^*Comparisons reaching statistical significance (P < 0.05).