Table 1. IC₅₀ values for inhibition of the binding of FAM-p4 to hDM2 and hDMX of small molecules. ^a A green background indicates the compound was designed for and was selective to the same protein. Yellow indicates the compound is a dual inhibitor. A red background indicates the compound was designed for one protein but was selective for the other protein.

^aIC₅₀ values determined by non-linear regression of at least three independent experiments (see ESI,† pg 10). Errors are 95% confidence intervals (CI). Fmoc, 9-fluorenylmethylcarbonyl.