Table 1.

Effects of Serotonin and Dopamine Receptor Agonists on Resting Hemodynamic Parameters

Drugs					Resting parameters
Name	Type	Delivery	Con. (μg/kg)	Animals (n)	MAP	HR
8-OH-DPAT	5-HT1A agonist	s.c.	Basal	4	109.2 ± 2.8	476 ± 17
			Low (5.0)		106.7 ± 4.0	487 ± 15
			Mid (20)		107.0 ± 3.8	484 ± 16
			High (100)		104.1 ± 7.6	396 ± 23
DOI	5-HT2A agonist		Basal	9	106.3 ± 3.2	448 ± 19
			Low (5.0)		116.4 ± 3.6**	467 ± 21
			Mid (20)		132.5 ± 3.9**	440 ± 16
			High (100)		146.5 ± 8.8**	425 ± 18
DOI	5-HT2A agonist	i.t.	Basal	4	92.2 ± 2.7	339 ± 18
			Low (1.0)		97.1 ± 1.7	341 ± 17
			Mid (4.0)		104.1 ± 1.1*	342 ± 11
			High (20)		111.1 ± 3.6*	313 ± 12
Apomorphine	Non-selective DA receptor agonist	s.c.	Basal	7	102.8 ± 3.8	445 ± 24
			Low (10)		104.9 ± 3.2	453 ± 21
			Mid (100)		106.0 ± 3.3	432 ± 17
			High (300)		101.7 ± 3.2	431 ± 11*

^*p < 0.05, ^**p < 0.01, repeated measures ANOVA followed by Fisher's PLSD.

ANOVA, analysis of variance; DOI, Dimethoxy-4-iodoamphetamine; i.t., intrathecal; HR, heart rate; MAP, mean arterial pressure; s.c., subcutaneous.