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. 2019 Apr 10;34(3):147–159. doi: 10.1089/cbr.2018.2628

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© Massimo Fantini, et al., 2019; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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FIG. 5. — ALT-803 prolongs viability of NK cells. Purified NK cells from two healthy donors were treated with ALT-803 (25 ng/mL) or vehicle control at the day 0 and then returned to incubation for 6 d. NK cell viability was analyzed on day 1, 2, 3, 4, and 6 post-treatment (A, B). Purified NK cells from two healthy donors were treated with ALT-803 (25 ng/mL) or vehicle control for 10 d. ALT-803 and vehicle control were replenished every 2 d. NK cell viability was analyzed on day 1, 2, 4, 8, and 10 post-treatment (C, D). Results are presented as mean ± S.E.M. from three replicate wells. p-Values denote statistical significance relative to untreated cells (T-test). NK, natural killer.